Abstract | OBJECTIVE: METHODS: All charts of patients meeting DSM-IV criteria for bipolar disorder treated with galantamine in an academic bipolar disorder specialty clinic psychiatric practice were reviewed and clinical response was assessed retrospectively using the Clinical Global Impression scale for Improvement. RESULTS:
Galantamine was effective in two of four patients, both of whom took at least 24 mg/day. It was ineffective in two patients who only took 8 mg/day. Sedation limited higher dosing in one patient, and a second patient experienced sedation and tremor. Improvement in cognition was not associated with improvement in mood. Galantamine appeared neutral in its effect on mood. CONCLUSIONS:
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Authors | Eric Schrauwen, S Nassir Ghaemi |
Journal | Bipolar disorders
(Bipolar Disord)
Vol. 8
Issue 2
Pg. 196-9
(Apr 2006)
ISSN: 1398-5647 [Print] Denmark |
PMID | 16542191
(Publication Type: Case Reports, Journal Article, Research Support, N.I.H., Extramural)
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Chemical References |
- Cholinesterase Inhibitors
- Galantamine
|
Topics |
- Adult
- Bipolar Disorder
(complications)
- Cholinesterase Inhibitors
(therapeutic use)
- Cognition Disorders
(drug therapy, etiology)
- Female
- Galantamine
(therapeutic use)
- Humans
- Male
- Middle Aged
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