Lepirudin for cardiopulmonary bypass surgery in a patient with terminal renal insufficiency and acute heparin-induced thrombocytopenia.

Abstract	A patient with triple heart valve disease, heparin-induced thrombocytopenia, and terminal renal insufficiency was treated successfully using lepirudin for anticoagulation of cardiopulmonary bypass (CPB) and during the postoperative course. Anticoagulatory monitoring was performed with ecarin clotting time during CPB and aPTT postoperatively.
Authors	F-C Riess, B Dobritzsch, J Kormann
Journal	The Thoracic and cardiovascular surgeon (Thorac Cardiovasc Surg) Vol. 54 Issue 2 Pg. 140-2 (Mar 2006) ISSN: 0171-6425 [Print] Germany
PMID	16541359 (Publication Type: Case Reports, Journal Article)
Chemical References	Anticoagulants Hirudins Recombinant Proteins Heparin lepirudin
Topics	Aged Anticoagulants (adverse effects, therapeutic use) Cardiopulmonary Bypass (methods) Female Follow-Up Studies Heart Failure (complications, surgery) Heparin (adverse effects) Hirudins Humans Kidney Failure, Chronic (complications) Myocardial Ischemia (surgery) Recombinant Proteins (therapeutic use) Thrombocytopenia (chemically induced, complications)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!