Abstract | BACKGROUND: METHODS: RESULTS: HOMA-IR in the GP group was significantly decreased compared to the GB group. Plasma adiponectin levels were significantly increased in the GP group but not in the other groups. TNF-alpha, interleukin-6 and high sensitive-CRP levels were significantly decreased in the GP group, but not in the other groups. The baPWV and AI levels did not change in either the GB or the INS group, but were significantly decreased in the GP group. CONCLUSIONS:
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Authors | Kunihiko Koshiba, Masahiro Nomura, Yutaka Nakaya, Susumu Ito |
Journal | The journal of medical investigation : JMI
(J Med Invest)
Vol. 53
Issue 1-2
Pg. 87-94
(Feb 2006)
ISSN: 1343-1420 [Print] Japan |
PMID | 16538000
(Publication Type: Journal Article, Randomized Controlled Trial)
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Chemical References |
- Cytokines
- Hypoglycemic Agents
- Inflammation Mediators
- Sulfonylurea Compounds
- glimepiride
- Glyburide
|
Topics |
- Adipocytes
(drug effects)
- Aged
- Atherosclerosis
(drug therapy, physiopathology)
- Cytokines
(blood)
- Diabetes Mellitus, Type 2
(drug therapy, physiopathology)
- Female
- Glyburide
(therapeutic use)
- Humans
- Hypoglycemic Agents
(therapeutic use)
- Inflammation Mediators
(blood)
- Insulin Resistance
- Male
- Metabolic Syndrome
(drug therapy, physiopathology)
- Middle Aged
- Sulfonylurea Compounds
(therapeutic use)
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