[A case of small-cell lung cancer responding remarkably to CPT-11 and CDDP combination chemotherapy].

Abstract

A 73-year-old man was admitted to our hospital complaining of general malaise, loss of appetite and body weight loss. Chest X-ray film showed left-sided pleural effusion. Computed tomographic (CT) scan of the chest also demonstrated left-sided pleural effusion with lung tumor and lymphnode swelling. Repeated treatment with 60 mg/m(2) of cisplatin on day 1 followed by 80 mg/m(2) of irinotecan on days 1 and 8 were effective in this patient.

• Authors: Yoshihisa Ishiura, Yasushi Terasaki, Hiroyuki Nakamura, Shigeru Yokawa, Katsuhiko Saito, Kazuo Kasahara, Masaki Fujimura
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 33 Issue 3 Pg. 369-71 (Mar 2006) ISSN: 0385-0684 [Print] Japan
• PMID: 16531721 (Publication Type: Case Reports, Journal Article)

Chemical References

• Irinotecan
• Cisplatin
• Camptothecin

Topics

• Aged
• Antineoplastic Combined Chemotherapy Protocols (therapeutic use)
• Camptothecin (administration & dosage, analogs & derivatives)
• Carcinoma, Small Cell (diagnostic imaging, drug therapy)
• Cisplatin (administration & dosage)
• Cranial Irradiation
• Drug Administration Schedule
• Humans
• Irinotecan
• Lung Neoplasms (diagnostic imaging, drug therapy)
• Male
• Neoplasm Metastasis (prevention & control)
• Pleural Effusion, Malignant (drug therapy)
• Remission Induction
• Tomography, X-Ray Computed