Abstract |
We present two patients who developed keratitis sicca and pemphigoid-like symptoms following allogeneic bone marrow transplantation (BMT). The diagnosis of ocular graft-versus-host disease (GvHD) was considerably delayed in both. They were admitted to the reference ophthalmology and posttransplant care departments years after allogeneic BMT, when skin biopsy revealed changes typical for chronic GvHD. In both cases either systemic or local immunosuppressive treatment led to improvement of the clinical condition but did not significantly change patients' quality of life.
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Authors | E Karwacka, U Ołdakowska-Jedynak, J Brydak-Godowska, L Paczek, D Kecik |
Journal | Transplantation proceedings
(Transplant Proc)
2006 Jan-Feb
Vol. 38
Issue 1
Pg. 292-4
ISSN: 0041-1345 [Print] United States |
PMID | 16504728
(Publication Type: Case Reports, Journal Article)
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Chemical References |
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Topics |
- Adult
- Bone Marrow Transplantation
(adverse effects)
- Eye Diseases
(etiology)
- Female
- Graft vs Host Disease
(drug therapy, etiology)
- Humans
- Immunosuppressive Agents
(therapeutic use)
- Male
- Pemphigoid, Bullous
(etiology)
- Skin
(pathology)
- Transplantation, Homologous
- Treatment Outcome
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