[Sub-Tenon's injection of triamcinolone acetonide for choroidal neovascularization].

Abstract

PURPOSE:

To evaluate the efficacy of sub-Tenon's injection of triamcinolone acetonide for age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV).

METHOD:

Sub-Tenon's injection of triamcinolone acetonide was performed in patients (27 eyes) with the subfoveal choroidal neovascularization of AMD and in patients (10 eyes) with PCV, and its efficacy was evaluated. The visual acuity and the exudation from lesions evaluated by fluorescein angiography or optical coherence tomography (OCT) at three months or six months after injection were compared to the baseline values.

RESULTS:

Visual acuity was maintained in 23 of the 27 eyes (85.0%) with AMD and in 8 of the 10 eyes (80.0%) with PCV at three months after injection. Six months after infusion, the rate declined to 76.0% and 66.7%, respectively. Exudation from lesions had decreased in 10 eyes of 25 eyes(40.0%) with AMD and in 2 eyes of 9 eyes (22.2%) with PCV by six months after injection. Complete suppression of the lesions was observed in seven eyes (18.9%) with relatively small lesions.

CONCLUSION:

Sub-Tenon's injection of triamcinolone acetonide is useful as a treatment modality for AMD and PCV.

• Authors: Aya Kim, Fumi Gomi, Hirokazu Sakaguchi, Yusuke Oshima, Yasushi Ikuno, Motohiro Kamei, Masahito Oji, Yasuo Tano
• Journal: Nippon Ganka Gakkai zasshi (Nippon Ganka Gakkai Zasshi) Vol. 110 Issue 1 Pg. 19-24 (Jan 2006) ISSN: 0029-0203 [Print] Japan
• PMID: 16491869 (Publication Type: English Abstract, Journal Article)

Chemical References

• Glucocorticoids
• Triamcinolone Acetonide

Topics

• Aged
• Choroidal Neovascularization (drug therapy)
• Female
• Glucocorticoids (administration & dosage)
• Humans
• Injections
• Male
• Middle Aged
• Triamcinolone Acetonide (administration & dosage)
• Visual Acuity