Abstract |
We report on the case of a patient with a diagnosis of an uncommon breast tumour, namely a radiation-induced angiosarcoma, which was primarily refractory to anthracycline-based chemotherapy, but highly sensitive to docetaxel. Although the sarcomas in general tend to be relatively refractory to taxanes, there is some evidence that the angiosarcomas may be sensitive to these agents. This is particularly well documented with paclitaxel, but may also be the case with docetaxel.
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Authors | Max S Mano, Ghislaine Fraser, Janet Kerr, Maureen Gray, Vicky Evans, Ather Kazmi, Peter Canney |
Journal | Breast (Edinburgh, Scotland)
(Breast)
Vol. 15
Issue 1
Pg. 117-8
(Feb 2006)
ISSN: 0960-9776 [Print] Netherlands |
PMID | 16473744
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Antineoplastic Agents, Phytogenic
- Taxoids
- Docetaxel
- Epirubicin
- Cyclophosphamide
- Fluorouracil
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Topics |
- Aged
- Antineoplastic Agents, Phytogenic
(therapeutic use)
- Antineoplastic Combined Chemotherapy Protocols
(therapeutic use)
- Breast Neoplasms
(drug therapy, etiology)
- Cyclophosphamide
(administration & dosage)
- Docetaxel
- Drug Resistance, Neoplasm
- Epirubicin
(administration & dosage)
- Female
- Fluorouracil
(administration & dosage)
- Hemangiosarcoma
(drug therapy, etiology)
- Humans
- Neoplasms, Radiation-Induced
(drug therapy)
- Taxoids
(therapeutic use)
- Treatment Outcome
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