Abstract |
We present an unusual case of extracranial metastasis of glioblastoma multiforme (GBM) to the parotid gland and cervical lymph nodes. The patient had previously undergone two craniotomies to debulk a left frontal GBM, followed by radiotherapy. After the second craniotomy, while waiting for chemotherapy, the patient was re-admitted with a short history of a painful swelling of his left parotid gland. The initial diagnosis was infective parotitis; however, as there was no improvement with broad-spectrum antibiotics, CT was undertaken, which revealed a mass in the parotid gland with a necrotic centre and enlarged cervical lymph nodes. Parotid gland biopsy revealed a parotid GBM metastasis. This case illustrates how GBM behaves in an aggressive manner even outside the CNS. A brief review of the literature and of the theories, which might explain the extra-neural metastasis of this tumour is also presented.
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Authors | M Taha, A Ahmad, S Wharton, D Jellinek |
Journal | British journal of neurosurgery
(Br J Neurosurg)
Vol. 19
Issue 4
Pg. 348-51
(Aug 2005)
ISSN: 0268-8697 [Print] England |
PMID | 16455543
(Publication Type: Case Reports, Journal Article)
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Topics |
- Acute Disease
- Adult
- Brain Neoplasms
(pathology)
- Fatal Outcome
- Glioblastoma
(pathology, secondary)
- Humans
- Magnetic Resonance Imaging
- Male
- Parotid Neoplasms
(diagnostic imaging, secondary)
- Parotitis
(etiology)
- Tomography, X-Ray Computed
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