[Hyperkalemia caused by intravenous administration of mannitol in a patient with arteriovenous malformation: case report].

Abstract

We experienced a case in which hyperkalemia was induced by mannitol administration. The medication with mannitol was given to a 15-year-old male patient who underwent a removal operation for arteriovenous malformation under general anesthesia. Following the mannitol infusion, his arterial blood gas and electrolyte analysis revealed severe metabolic acidosis and an increase in serum potassium. Furthermore, a change in his electrocardiogram was observed. The hyperkalemia was quickly normalized by medication with calcium gluconate and sodium bicarbonate. We stopped the removal operation with the aim of giving priority to the patient's safety. It is speculated that the hyperkalemia was caused by the administration of mannitol. Checks of electrolyte levels, arterial blood gas analysis and electrocardiogram monitoring should therefore be carried out when using mannitol, especially in an emergency situation such as intracranial hemorrhage.

• Authors: Shigeyoshi Kimura, Haruhiko Ogawa, Yoichi Katayama
• Journal: No shinkei geka. Neurological surgery (No Shinkei Geka) Vol. 34 Issue 1 Pg. 51-6 (Jan 2006) ISSN: 0301-2603 [Print] Japan
• PMID: 16440697 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Diuretics, Osmotic
• Mannitol

Topics

• Acidosis (chemically induced)
• Adolescent
• Arteriovenous Malformations (surgery)
• Diuretics, Osmotic (adverse effects)
• Electrocardiography (drug effects)
• Humans
• Hyperkalemia (chemically induced)
• Intraoperative Complications
• Male
• Mannitol (adverse effects)
• Neurosurgical Procedures