Abstract |
Uterine myomas are common but erythrocytosis caused by these is rarely seen. We report a case that illustrates the conjunction of various aetiological factors required for this clinical entity to evolve. A voluminous, retroperitoneally located and focally degenerated myoma was associated with severe secondary erythrocytosis (haematocrit: 65.5%) which resolved after hysterectomy. It has been demonstrated previously that myomatous tissue is the source of excessive production of erythropoietin. Local tissue hypoxia, which is more prone to develop in a pedunculated myoma, stimulates the process. Other prerequisites are a very large size of the myoma and the absence of menometrorrhagia of a severity such as to cause a depletion in iron reserves.
|
Authors | Christophe Blockeel, Bart Op De Beeck, Claire Bourgain, Jean-Jacques Amy |
Journal | The National medical journal of India
(Natl Med J India)
2005 Sep-Oct
Vol. 18
Issue 5
Pg. 247-9
ISSN: 0970-258X [Print] India |
PMID | 16433138
(Publication Type: Case Reports, Journal Article)
|
Chemical References |
- Receptors, Erythropoietin
- Erythropoietin
|
Topics |
- Adult
- Erythropoietin
(metabolism)
- Female
- Humans
- Immunohistochemistry
- Leiomyoma
(diagnosis, diagnostic imaging)
- Polycythemia
(diagnosis, diagnostic imaging)
- Receptors, Erythropoietin
(metabolism)
- Syndrome
- Ultrasonography
- Uterine Neoplasms
(diagnosis, diagnostic imaging)
|