[The phospholipid spectrum of erythrocyte membranes in hemorrhagic fever with renal syndrome].

The subjects of the study--patients with severe hemorrhagic fever with renal syndrome--were divided into two groups: those who were on hemodialysis, and those who were not. The study included evaluation of the phospholipid spectrum of erythrocyte membranes in the acute period and during recovery. The results revealed conformational shifts in the structure of the bilipid membrane layer, which were maximal during the acute phase of the disease, as well as less prominent and varied changes in the phospholipid spectrum during recovery. This allows determination of the terms of rehabilitation of the patients and substantiates administration of membrane stabilizers as a part of complex therapy of residual syndrome.
AuthorsV I Kuznetsov, N D Iushchuk, V V Morrison
JournalKlinicheskaia meditsina (Klin Med (Mosk)) Vol. 83 Issue 11 Pg. 49-52 ( 2005) ISSN: 0023-2149 [Print] Russia (Federation)
PMID16404940 (Publication Type: Comparative Study, English Abstract, Journal Article)
Chemical References
  • Biomarkers
  • Phospholipids
  • Biomarkers (metabolism)
  • Chromatography, Thin Layer
  • Disease Progression
  • Erythrocyte Membrane (metabolism)
  • Follow-Up Studies
  • Hemorrhagic Fever with Renal Syndrome (blood, therapy)
  • Humans
  • Phospholipids (metabolism)
  • Remission Induction
  • Renal Dialysis
  • Severity of Illness Index

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