Psychopathological and cognitive correlates of tardive dyskinesia in patients treated with neuroleptics.

Abstract

Even though new cases of TD are on the decline in North America and other western countries, TD remains a public health concern for patients with chronic schizophrenia, PAD, and for nonpsychiatric patients treated with dopamine receptor antagonists. The new generation of atypical antipsychotic medications is believed to pose less risk for TD. However, identifying the cognitive and disease-related correlates of TD should equip clinicians with the necessary tools to reduce the prevalence of this iatrogenic movement disorder. No effective treatments for TD are available. This lack of effective therapy is problematic, especially in the few patients in whom the disorder causes functional impairment and other complications, and in whom it may be irreversible.

• Authors: Ikwunga Wonodi, L Elliot Hong, Gunvant K Thaker
• Journal: Advances in neurology (Adv Neurol) Vol. 96 Pg. 336-49 ( 2005) ISSN: 0091-3952 [Print] United States
• PMID: 16383230 (Publication Type: Journal Article, Research Support, N.I.H., Extramural, Research Support, U.S. Gov't, Non-P.H.S., Review)

Chemical References

• Antipsychotic Agents

Topics

• Affective Disorders, Psychotic (complications, drug therapy)
• Akathisia, Drug-Induced (complications, drug therapy)
• Antipsychotic Agents (therapeutic use)
• Cognition (drug effects)
• Humans
• Psychopathology