Sweet's syndrome responding to cyclosporin.

Abstract

We report a case of Sweet's syndrome which responded to treatment with cyclosporin 4 mg/kg/day. Cyclosporin is effective in the treatment of many dermatoses, and although the immunosuppressive effects of cyclosporin are mainly attributed to inhibition of T-lymphocyte proliferation, it has also been shown to affect the functions of both neutrophils and monocytes. Possible mechanisms of action of cyclosporin in Sweet's syndrome are discussed.

• Authors: J F Bourke, J Berth-Jones, R A Graham-Brown
• Journal: The British journal of dermatology (Br J Dermatol) Vol. 127 Issue 1 Pg. 36-8 (Jul 1992) ISSN: 0007-0963 [Print] England
• PMID: 1637692 (Publication Type: Case Reports, Journal Article)

Chemical References

• Cyclosporine

Topics

• Adult
• Biopsy
• Cyclosporine (therapeutic use)
• Female
• Humans
• Skin (pathology)
• Sweet Syndrome (drug therapy, pathology)