An update on the use of ophthalmic ketorolac tromethamine 0.4%.

Abstract

Ketorolac tromethamine 0.4% ophthalmic solution, a recent reformulation of the original ketorolac tromethamine 0.5% solution, is indicated for the reduction of ocular pain and burning/stinging following cataract and refractive surgery. Studies have demonstrated that ketorolac tromethamine 0.4% has equivalent efficacy to ketorolac tromethamine 0.5% in reducing postsurgical inflammation and controlling pain. Several studies have demonstrated that, as well as reducing pain and ocular inflammation, ketorolac tromethamine 0.4% effectively treats cystoid macular oedema, inhibits miosis and may prevent cystoid macular oedema when used both pre- and postoperatively. Ketorolac tromethamine 0.4% is a versatile agent and is effective when used as either monotherapy or as an adjunct therapy to steroids.

• Authors: Henry D Perry, Eric D Donnenfeld
• Journal: Expert opinion on pharmacotherapy (Expert Opin Pharmacother) Vol. 7 Issue 1 Pg. 99-107 (Jan 2006) ISSN: 1744-7666 [Electronic] England
• PMID: 16370927 (Publication Type: Journal Article, Review)

Chemical References

• Anti-Inflammatory Agents, Non-Steroidal
• Prostaglandins
• Ketorolac Tromethamine

Topics

• Administration, Topical
• Animals
• Anti-Inflammatory Agents, Non-Steroidal (administration & dosage)
• Eye Diseases (drug therapy, metabolism)
• Humans
• Ketorolac Tromethamine (administration & dosage)
• Prostaglandins (biosynthesis)
• Uveitis, Anterior (drug therapy, metabolism)