Abstract |
This chapter focuses on cell replacement therapies in Parkinson's disease (PD) and describes experimental data leading to clinical trials, as well as the methodology and efficacy of grafts of human embryonic nigral tissue in patients with PD. It also highlights some of the clinical problems the procedure presents and considers future alternative sources of donor tissue, including various forms of stem cells.
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Authors | G Paul |
Journal | Handbook of experimental pharmacology
(Handb Exp Pharmacol)
Issue 174
Pg. 361-88
( 2006)
ISSN: 0171-2004 [Print] Germany |
PMID | 16370335
(Publication Type: Journal Article, Review)
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Chemical References |
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Topics |
- Animals
- Brain Tissue Transplantation
- Controlled Clinical Trials as Topic
- Dopamine
(metabolism)
- Humans
- Parkinson Disease
(drug therapy, pathology, surgery)
- Stem Cell Transplantation
- Stem Cells
(cytology, metabolism)
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