Struma ovarii showing clinical characteristics of ovarian malignancy.

Abstract

Struma ovarii is a rare form of ovarian neoplasm, composed entirely or predominantly of thyroid tissue and generally a benign germ cell tumor of the ovary. Ascites have been reported in approximately 15-20% of all cases. However, the combination of struma ovarii and elevated CA125 has rarely been reported. We experienced a rare case of a postmenopausal woman with benign struma ovarii associated with massive ascites, a complex pelvic mass. There was marked elevation of her CA125 level. The clinical impression was ovarian malignancy. Surgical excision of the ovarian mass induced immediate resolution of the ascites and a normalization of the serum CA125 level. No recurrence of the ascites or of the tumor has been observed during the 10-month follow-up. Struma ovarii can mimic ovarian malignancy clinically, particularly if complex and associated with ascites and an elevated CA125 level.

• Authors: S Y Rim, S M Kim, H S Choi
• Journal: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society (Int J Gynecol Cancer) Vol. 15 Issue 6 Pg. 1156-9 ( 2005) ISSN: 1048-891X [Print] England
• PMID: 16343201 (Publication Type: Case Reports, Journal Article)

Chemical References

• Biomarkers, Tumor
• CA-125 Antigen

Topics

• Ascites (etiology)
• Biomarkers, Tumor (blood)
• CA-125 Antigen (blood)
• Female
• Gynecologic Surgical Procedures
• Humans
• Middle Aged
• Ovarian Neoplasms (blood, complications, pathology, surgery)
• Struma Ovarii (blood, complications, pathology, surgery)
• Teratoma (pathology, surgery)