Electrophysiologic findings in optic nerve dysfunction associated with multiple evanescent white-dot syndrome.

Abstract

Electrophysiologic findings in a case of multiple evanescent white-dot syndrome were studied. A 37-year-old woman presented with multiple white dots, granularity of the macula, and optic disc swelling in her left fundus. The electroretinogram and electro-oculogram revealed abnormal findings indicative of changes in the retinal pigment epithelium and photoreceptors. In addition, relative afferent pupillary defect, enlargement of the blind spot, a decrease in the critical fusion frequency, staining of the optic disc on fluorescein angiography and prolonged latency of the P100 component with decreased amplitude in pattern-reversal visual evoked cortical potential strongly suggested dysfunction of the optic nerve in this patient.

• Authors: N Takeda, K Numata, S Yamamoto, T Katayama, Y Kubota
• Journal: Documenta ophthalmologica. Advances in ophthalmology (Doc Ophthalmol) Vol. 79 Issue 4 Pg. 295-302 ( 1992) ISSN: 0012-4486 [Print] Netherlands
• PMID: 1633741 (Publication Type: Case Reports, Journal Article)

Topics

• Adult
• Dark Adaptation
• Electroretinography
• Evoked Potentials, Visual
• Female
• Fluorescein Angiography
• Fundus Oculi
• Humans
• Optic Nerve Diseases (physiopathology)
• Pattern Recognition, Automated
• Photic Stimulation
• Pigment Epithelium of Eye (physiopathology)
• Retinal Diseases (physiopathology)
• Syndrome
• Visual Fields