A randomised study of "wet wraps" versus conventional treatment for atopic eczema.

Abstract

AIMS:

To compare two treatments in common usage for children with atopic eczema: "wet wrap" bandages versus conventional topically applied ointments.

METHODS:

A total of 50 children (age 4-27 months) with moderate to severe eczema were randomised to one or other treatment. Two research nurses supervised the study. The first gave advice and support, and the second, blinded to the treatment modality being used, scored the change in eczema severity over a period of four weeks using the SCORAD eczema severity scale.

RESULTS:

Both treatments gave a benefit in overall SCORAD scores (mean change for wet wrap group was 53 to 24; for the conventional group, 41 to 17). There was no significant difference between the two groups in terms of overall improvement at four weeks or in the timescale of improvements. The amount of topical of topical steroid used was similar in both groups. The wet wrap group suffered significantly more skin infections requiring antibiotics. Carers reported that wet wraps were less easy to apply than conventional treatment.

• Authors: D Hindley, G Galloway, J Murray, L Gardener
• Journal: Archives of disease in childhood (Arch Dis Child) Vol. 91 Issue 2 Pg. 164-8 (Feb 2006) ISSN: 1468-2044 [Electronic] England
• PMID: 16308411 (Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)

Chemical References

• Anti-Inflammatory Agents
• Emollients
• Glucocorticoids
• Water
• Hydrocortisone

Topics

• Administration, Cutaneous
• Anti-Inflammatory Agents (therapeutic use)
• Bandages
• Child, Preschool
• Dermatitis, Atopic (drug therapy, therapy)
• Emollients (therapeutic use)
• Female
• Glucocorticoids (therapeutic use)
• Humans
• Hydrocortisone (therapeutic use)
• Infant
• Male
• Severity of Illness Index
• Single-Blind Method
• Treatment Outcome
• Water