Abstract | STUDY OBJECTIVE: To analyze whether emergence agitation could be reduced by using a low dosage of fentanyl without causing an increase in postoperative adverse effects and/or affecting the patient's quality of life after discharge. DESIGN: Randomized, controlled crossover trial. SETTING: University medical center. PATIENTS: INTERVENTIONS: During their first visit, patients were randomly treated either with a placebo or a 1- to 1.5-microg/kg dose of fentanyl before inserting a reinforced laryngeal mask airway and treated with the remaining method during their second visit 6 to 12 months later. MEASUREMENTS: Measured variables included anesthetic and emergence period, the occurrence of emergence agitation, and postanesthetic adverse effects such as nausea and vomiting. After discharge, the patient's quality of life was evaluated based on disturbances in daily activity, eating habit, and sleeping behavior. Results were analyzed by Student t test and McNemar test (P < 0.05). MAIN RESULTS: Between the two treatments, there was a significant difference in the frequency of emergence agitation (P = 0.04) but no postoperative adverse effects such as postoperative nausea and vomiting. We also found no significant disturbances in the patient's quality of life according to daily activity, eating habits, or sleeping behavior. CONCLUSION:
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Authors | Wei-Te Hung, Ching-Chi Chen, Cher-Ming Liou, Wei-Yann Tsai |
Journal | Journal of clinical anesthesia
(J Clin Anesth)
Vol. 17
Issue 7
Pg. 494-8
(Nov 2005)
ISSN: 0952-8180 [Print] United States |
PMID | 16297747
(Publication Type: Journal Article, Randomized Controlled Trial)
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Chemical References |
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Topics |
- Adolescent
- Adult
- Anesthesia
(adverse effects)
- Anesthesia Recovery Period
- Child
- Child, Preschool
- Dental Care
- Developmental Disabilities
(complications, psychology)
- Double-Blind Method
- Female
- Fentanyl
(administration & dosage, therapeutic use)
- Humans
- Laryngeal Masks
- Male
- Narcotics
(administration & dosage, therapeutic use)
- Postoperative Complications
(chemically induced, psychology)
- Postoperative Nausea and Vomiting
(complications, psychology)
- Psychomotor Agitation
(prevention & control)
- Quality of Life
(psychology)
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