Abstract | INTRODUCTION: METHODS: We compared the prevalence of depressive symptomatology in elderly outpatients with stable disabling COPD with that in healthy controls and age-matched patients with other disabilities, and also assessed the relation between degree of disability, quality of life and depressive symptoms. The subjects were 96 older people with COPD [56 men; aged 70-93 (mean 78) years], 55 normal controls [23 men; aged 70-90 (mean 78) years] and 53 disabled controls [27 men; aged 70-92 (mean 78) years]. Exclusion criteria were acute respiratory exacerbation or use of oral steroids in the last 6 weeks, known previous psychiatric disorder and acute or chronic confusion. RESULTS: Mean (and SD) values for 1-s forced expiratory volume (FEV1) were 51 (20) % in COPD subjects, 107 (24) % in normal controls and 82 (13)% in disabled controls. Forty-four subjects with COPD (46%), six normal controls (11%) and 14 disabled controls (26%) scored in the 'caseness' range for depressive ideation on the Brief Assessment Schedule Depression Cards (BASDEC) screening questionnaire. A multiple regression analysis was performed for the COPD group to identify factors predictive of BASDEC score. Predictive variables were total quality of life score [P<0.0001], Chronic Respiratory Questionnaire and level of activities of daily living (Nottingham extended activities of daily living scale) [P = 0.001]. Spirometry results and exercise tolerance (6-min walk distance) did not help predict BASDEC score (R2 = 0.50). CONCLUSIONS: Depressive symptoms are common in elderly patients with COPD; prevalence and/or severity of depressive symptoms may be greater in those who are most disabled.
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Authors | A M Yohannes, J Roomi, R C Baldwin, M J Connolly |
Journal | Age and ageing
(Age Ageing)
Vol. 27
Issue 2
Pg. 155-60
(Mar 1998)
ISSN: 0002-0729 [Print] England |
PMID | 16296675
(Publication Type: Journal Article)
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Topics |
- Aged
- Aged, 80 and over
- Depression
(epidemiology)
- Disability Evaluation
- Dyspnea
(epidemiology, psychology)
- Female
- Forced Expiratory Volume
- Humans
- Male
- Outpatients
(psychology, statistics & numerical data)
- Prevalence
- Pulmonary Disease, Chronic Obstructive
(epidemiology, psychology)
- Quality of Life
- Regression Analysis
- Severity of Illness Index
- Spirometry
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