Lung scintigraphy with [123I]IMP in patients with pulmonary tuberculosis.

Abstract

Lung scintigraphy using N-isopropyl-p-[123I]iodoamphetamine (IMP) was performed on 26 patients with pulmonary tuberculosis. Early (5 min after injection) and late images (4 h after injection) were obtained with a large-field gamma-camera equipped with a digital computer. Lung scintigraphy using [99mTc]MAA (MAA) was also done. Although early IMP images showed the same findings as [99mTc]MAA, images, a discrepancy between delayed IMP images and [99mTc]MAA images was seen in some patients. Increment of activities seen in late images was demonstrated in most patients whose chest x-ray findings included exudative inflammatory changes. Uptake and clearance of IMP was considered to be affected by the active phase of pulmonary tuberculosis.

• Authors: S Nagamachi, K Inoue, H Hoshi, S Jinnouchi, T Ohonishi, S Futami, K Watanabe, M Wakisaka, Y Morotomi
• Journal: International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology (Int J Rad Appl Instrum B) Vol. 19 Issue 3 Pg. 399-404 (Apr 1992) ISSN: 0883-2897 [Print] England
• PMID: 1629028 (Publication Type: Case Reports, Comparative Study, Journal Article)

Chemical References

• Amphetamines
• Iodine Radioisotopes
• Technetium Tc 99m Aggregated Albumin
• 4-iodoamphetamine

Topics

• Adult
• Aged
• Aged, 80 and over
• Amphetamines
• Female
• Humans
• Iodine Radioisotopes
• Lung (diagnostic imaging)
• Male
• Middle Aged
• Radionuclide Imaging (methods)
• Technetium Tc 99m Aggregated Albumin
• Tuberculosis, Pulmonary (diagnostic imaging)