HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Artificial iris-lens diaphragm in reconstructive surgery for aniridia and aphakia.

AbstractPURPOSE:
To determine the efficacy and safety of surgical implantation of artificial iris-lens diaphragm in patients with anatomic or functional iris deficiencies, aphakia or cataract.
SETTING:
Svyatoslav Fyodorov MNTK Eye Microsurgery, Cheboksary, Russia.
METHODS:
Twenty eyes of 19 consecutive patients with combined iris and lens pathology of traumatic or congenital etiology were identified for an interventional noncomparative case series. The newly proposed model of an elastic iris-lens diaphragm with a colored haptic and additional support elements was implanted using various fixation approaches.
RESULTS:
Fifteen eyes (75%) experienced improvement in corrected visual acuities. The best spectacle-corrected visual acuity (BSCVA) in 2 eyes did not change, while the uncorrected visual acuity (UCVA) in these eyes increased. There were 3 eyes in which BSCVA deteriorated with no change or even slight improvement in UCVA. All patients were satisfied with the cosmetic results of the surgery and reported a decrease in glare and photophobia. There was 1 intraoperative complication of vitreous hemorrhage. Postoperatively, 2 cases of hyphema, 1 case of ciliochoroidal detachment, 4 eyes with exaggerated immediate postoperative reaction, and 1 eye with persistent low-grade cyclitis were observed. In 1 eye, there was persistent intraocular pressure rise. One eye showed signs of cystoid macular edema. No iris-lens diaphragm decentrations and no new or extensions of old retinal detachments were seen during the follow-up period.
CONCLUSIONS:
Artificial iris-lens diaphragm implantation effectively improved postoperative outcomes by correcting aphakia, reducing glare disability, and addressing cosmetic issues faced by iris-deficient, and aphakic or cataract patients. Although the iris-lens diaphragm appears to be safe, long-term results must be clarified in studies with longer follow-up and a larger patient population.
AuthorsNadezhda A Pozdeyeva, Nikolay P Pashtayev, Vladislav P Lukin, Yevgeniy N Batkov
JournalJournal of cataract and refractive surgery (J Cataract Refract Surg) Vol. 31 Issue 9 Pg. 1750-9 (Sep 2005) ISSN: 0886-3350 [Print] United States
PMID16246779 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Topics
  • Adolescent
  • Adult
  • Aniridia (surgery)
  • Aphakia, Postcataract (surgery)
  • Artificial Organs
  • Female
  • Humans
  • Intraoperative Complications
  • Iris
  • Lens, Crystalline
  • Lenses, Intraocular
  • Male
  • Middle Aged
  • Ophthalmologic Surgical Procedures (methods)
  • Postoperative Complications
  • Prosthesis Implantation
  • Plastic Surgery Procedures (methods)
  • Visual Acuity

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: