Successful thrombolytic therapy for prosthetic mitral valve thrombosis with hemodynamic obstruction: case report and review of the literature.

Abstract

Prosthetic valve thrombosis (PVT) is a serious complication of mechanical valves. The use of thrombolytic therapy to relieve thrombotic prosthetic valve obstruction is accepted for right-sided valves, but its role in left-sided valves and hemodynamically stable patients awaits clarification. The case is presented of a patient in whom prosthetic heart valve thrombosis was treated successfully with streptokinase under transesophageal echocardiographic guidance.

• Authors: Bahri Akdeniz, Nezihi Baris, Ozer Badak, Ozgür Aslan
• Journal: The Journal of heart valve disease (J Heart Valve Dis) Vol. 14 Issue 5 Pg. 687-92 (Sep 2005) ISSN: 0966-8519 [Print] England
• PMID: 16245509 (Publication Type: Case Reports, Journal Article, Review)

Chemical References

• Fibrinolytic Agents
• Streptokinase

Topics

• Echocardiography
• Echocardiography, Transesophageal
• Female
• Fibrinolytic Agents (therapeutic use)
• Heart Valve Prosthesis
• Humans
• Middle Aged
• Mitral Valve Stenosis (diagnostic imaging, physiopathology, therapy)
• Prosthesis Failure
• Rheumatic Heart Disease (diagnostic imaging, physiopathology, therapy)
• Streptokinase (therapeutic use)
• Thrombolytic Therapy