Abstract | BACKGROUND: METHODS: A Medline search was performed and all relevant English language articles published between 1970 and 2005 were retrieved. The search words included ' parathyroid carcinoma', 'pathology', 'genetics', 'management' and ' radiotherapy'. Secondary references were obtained from key articles. RESULTS AND CONCLUSION: The exact aetiology of parathyroid carcinoma remains obscure. Recently, the HRPT2 gene has been implicated in its pathogenesis and may prove to be a genetic target in future. Surgical resection is the accepted 'gold standard'. There is now a growing consensus on the use of adjuvant radiotherapy as it has been shown to provide a survival benefit.
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Authors | N Rawat, N Khetan, D W Williams, J N Baxter |
Journal | The British journal of surgery
(Br J Surg)
Vol. 92
Issue 11
Pg. 1345-53
(Nov 2005)
ISSN: 0007-1323 [Print] England |
PMID | 16237743
(Publication Type: Journal Article, Review)
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Topics |
- Combined Modality Therapy
- Humans
- Neoplasm Recurrence, Local
(therapy)
- Parathyroid Neoplasms
(diagnosis, etiology, therapy)
- Treatment Outcome
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