Abstract | OBJECTIVE: This study was undertaken to compare the quality of life (QoL) in women with early stage endometrial cancer treated with 2 different surgical approaches. STUDY DESIGN: Eighty-four women with clinical stage I endometrial cancer were enrolled in a prospective randomized controlled trial design and treated with laparoscopic or laparotomic approach. Another 40 women matched for demographic characteristics were studied as controls. In patients, before and after surgery, and in their matched controls, QoL was evaluated by using the Short-Form Healthy Survey (SF-36) and the climacteric symptoms using the Kupperman Index (KI). RESULTS: After randomization, no difference was detected in data recorded between the groups. At entry, QoL was similar in both treatment groups but significantly (P < .05) worse in comparison with controls. Throughout the study, QoL was significantly (P < .05) higher in laparoscopic group versus laparotomic group. After KI adjustment our data did not change. CONCLUSION:
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Authors | Fulvio Zullo, Stefano Palomba, Tiziana Russo, Angela Falbo, Marilena Costantino, Achille Tolino, Errico Zupi, Piersandro Tagliaferri, Salvatore Venuta |
Journal | American journal of obstetrics and gynecology
(Am J Obstet Gynecol)
Vol. 193
Issue 4
Pg. 1344-52
(Oct 2005)
ISSN: 1097-6868 [Electronic] United States |
PMID | 16202724
(Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial)
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Topics |
- Endometrial Neoplasms
(pathology, surgery)
- Female
- Humans
- Laparoscopy
- Laparotomy
- Middle Aged
- Neoplasm Staging
- Prospective Studies
- Quality of Life
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