This study was designed to evaluate the efficacy of local litholytic irrigation (LLI) in the treatment of ureteral
uric acid calculi. Fourteen cases of ureteral
uric acid calculi were diagnosed by abdominal plain radiography (KUB), retrograde urography, ultrasonography (B-mode ultrasound), spiral computerized tomography(CT) and blood biochemical examinations. A
ureteral catheter was passed retrogradely across
ureteral calculi by cystoscopy. LLI with
tromethamine-E (THAM-E) was performed via the
ureteral catheter after the improvement of renal function and general situation and the control of
urinary tract infection under the condition of intravenous application of
antibiotics. The irrigation rate varied from 1000 to 1500 ml per day. Retrograde pyelography demonstrated complete dissolution of all the stones, 13 cases within 10 days and 1 within 12 days. Mild
hematuria was observed in the majority of the cases and temporary aggravated
lumbago in 1 case, with no other side effects. It is concluded that LLI is a practical and effective method in the treatment of ureteral
uric acid calculi for its advantages of shorter duration,lower cost, less
physical suffering and no severe complications.