Abstract | OBJECTIVE: DESIGN: Cross-sectional analytical study. PLACE AND DURATION OF STUDY: Shaikh Zayed Postgraduate Medical Institute from November 2003 to August 2004. PATIENTS AND METHODS: Patients with cirrhosis and ascites underwent diagnostic paracentesis. Fluid was checked for leukocyte esterase released by PMN by using Combur 10 urine strip and graded for color change from 0-3. Fluid was also analyzed by cytology for PMN count. Results of both methods were compared to determine sensitivity, specificity and accuracy of strip for diagnosis of SBP. RESULTS: Of 214 paracentesis performed, SBP was diagnosed in 38 patients whereas 176 were negative for infection. Strip test was 97.7% sensitive and 89.4% specific with positive predictive value of 90%, negative predictive value of 97.7% and accuracy of 96.2%, when reagent strip grade 3 was considered as positive for diagnosis. CONCLUSION:
Reagent strip is a quick bedside test, highly sensitive and specific for the diagnosis of SBP, based on polymorphonuclear count in ascitic fluid, to initiate early treatment, thus improving patient's outcome.
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Authors | Shahid Sarwar, Altaf Alam, Mateen Izhar, Anwaar A Khan, Arshad Kamal Butt, Farzana Shafqat, Kashif Malik, Irfan Ahmed, Aamir Khan Niazi |
Journal | Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
(J Coll Physicians Surg Pak)
Vol. 15
Issue 7
Pg. 418-21
(Jul 2005)
ISSN: 1022-386X [Print] Pakistan |
PMID | 16197871
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Adult
- Cross-Sectional Studies
- Female
- Humans
- Male
- Middle Aged
- Peritonitis
(diagnosis, microbiology)
- Point-of-Care Systems
- Reagent Kits, Diagnostic
- Sensitivity and Specificity
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