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Acquired ichthyosis and hypertrichosis due to autoimmune thyroiditis: therapeutic response to thyroxine replacement.

Abstract
Thyroid diseases may be associated with a wide variety of dermatologic disorders. We report a 15-year-old girl with acquired ichthyosis and hypertrichosis associated with hypothyroidism resulting from autoimmune thyroiditis. Her skin lesions progressively resolved after 8 months of replacement therapy with L-thyroxine. This result supports the hypothesis that hypothyroidism in our patient can be directly related to the pathogenesis of acquired ichthyosis and hypertrichosis.
AuthorsValeria Brazzelli, Francesca Prestinari, Tania Barbagallo, Eleonora Bellani, Valeria Calcaterra, Daniella Larizza, Maria M Lauriola, Giovanni Borroni
JournalPediatric dermatology (Pediatr Dermatol) 2005 Sep-Oct Vol. 22 Issue 5 Pg. 447-9 ISSN: 0736-8046 [Print] United States
PMID16190999 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Hormones
  • Thyroxine
Topics
  • Adolescent
  • Female
  • Hormones (therapeutic use)
  • Humans
  • Hypertrichosis (drug therapy, etiology)
  • Hypothyroidism (drug therapy, etiology)
  • Ichthyosis (drug therapy, etiology)
  • Thyroiditis, Autoimmune (complications)
  • Thyroxine (therapeutic use)
  • Treatment Outcome

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