Water-generated negative air ions activate NK cell and inhibit carcinogenesis in mice.

Abstract

Negative ions are considered to have potential health benefits, but few studies have examined their effects in vivo. We studied water-generated negative ions (WNI) with respect to physical properties as well as immunologic activation and anti-tumor activity (inhibition of carcinogenesis and tumor growth) in mice. Electrically, generated negative ions (ENI) served as control. Water-generated negative ions had a long life, significantly enhanced the cytotoxic activity of natural killer cells, and significantly decreased the incidence of cancer and inhibited tumor growth. Anti-tumor effects were attributed to enhancement of natural killer cell activity. The mechanisms and applications of negative ions warrant further investigation.

• Authors: Roppei Yamada, Syunsuke Yanoma, Makoto Akaike, Akira Tsuburaya, Yukio Sugimasa, Shoji Takemiya, Hisahiko Motohashi, Yasushi Rino, Yoshinori Takanashi, Toshio Imada
• Journal: Cancer letters (Cancer Lett) Vol. 239 Issue 2 Pg. 190-7 (Aug 08 2006) ISSN: 0304-3835 [Print] Ireland
• PMID: 16171944 (Publication Type: Journal Article)

Chemical References

• Anions
• Water

Topics

• Animals
• Anions
• Cell Transformation, Neoplastic (immunology)
• Killer Cells, Natural (immunology)
• Mice
• Water