Cells in the respiratory and intestinal tracts of chickens have different proportions of both human and avian influenza virus receptors.

Abstract

Avian influenza viruses play a crucial role in the creation of human pandemic viruses. In this study, we have demonstrated that both human and avian influenza receptors exist in cells in the respiratory and intestinal tracts of chickens. We have also determined that primarily cultured chicken lung cells can support the replication of both avian and human influenza viruses.

• Authors: Jin A Kim, Si Yun Ryu, Sang Heui Seo
• Journal: Journal of microbiology (Seoul, Korea) (J Microbiol) Vol. 43 Issue 4 Pg. 366-9 (Aug 2005) ISSN: 1225-8873 [Print] Korea (South)
• PMID: 16145552 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Receptors, Virus

Topics

• Animals
• Cells, Cultured
• Chickens (metabolism)
• Colon (metabolism, virology)
• Flow Cytometry
• Humans
• Influenza A virus (metabolism, physiology)
• Lung (metabolism, virology)
• Receptors, Virus (biosynthesis, isolation & purification, metabolism)
• Virus Replication (physiology)