[Systemic corticosteroid therapy in non-arteritic anterior ischemic optic neuropathy].

Abstract

A non-arteritic anterior ischemic optic neuropathy has usually a poor prognosis. Spontaneous remissions are extremely rare. In contrast to arteritic anterior ischemic neuropathy, systemic corticosteroids are generally accepted to be ineffective. Two cases of bilateral severe non-arteritic anterior ischemic optic neuropathy are reported who underwent full remission of their visual function directly related to high-dose systemic corticosteroids. It is hypothesized that, in acute phases of non-arteritic anterior ischemic optic neuropathy a significant reduction of tissue swelling and consecutive prelaminar reperfusion can be achieved with high-dose corticosteroids.

• Authors: J Menzi, F Körner
• Journal: Klinische Monatsblatter fur Augenheilkunde (Klin Monbl Augenheilkd) Vol. 200 Issue 5 Pg. 349-53 (May 1992) ISSN: 0023-2165 [Print] Germany
• Vernacular Title: Systemische Kortikosteroidtherapie bei nicht-arteriitischer anteriorer ischämischer Optikusneuropathie.
• PMID: 1614099 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Prednisone

Topics

• Dose-Response Relationship, Drug
• Drug Administration Schedule
• Female
• Humans
• Intracranial Arteriosclerosis (complications, drug therapy)
• Ischemia (drug therapy)
• Middle Aged
• Optic Nerve (blood supply)
• Optic Neuritis (drug therapy)
• Prednisone (administration & dosage)
• Visual Acuity (drug effects)
• Visual Fields (drug effects)