HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Accumulation and depuration of paralytic shellfish poisoning toxins by laboratory cultured purple clam Hiatula diphos Linnaeus.

Abstract
Purple clams (Hiatula diphos Linnaeus) accumulate paralytic shellfish poisoning (PSP) toxins produced by a toxic strain of the dinoflagellate Alexandrium minutum Halim in a laboratory study. The maximal toxicity of PSP toxins attained 31.3m MU/g after 20 days exposure. The toxin profile of H. diphos was similar to that reported for A. minutum at the end of the exposure period; and GTX1 was dominant. GTX congeners were found in muscle on day 16 and day 20, these substances could be detected during the depuration period as well. GTX1 was detected in the siphon only on day 32. The results show that H. diphos accumulates PSP toxins according to the amount and toxin profile of ingested A. minutum.
AuthorsHong Nong Chou, Chen Ping Huang, Chih Yu Chen
JournalToxicon : official journal of the International Society on Toxinology (Toxicon) Vol. 46 Issue 5 Pg. 587-90 (Oct 2005) ISSN: 0041-0101 [Print] England
PMID16137734 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Marine Toxins
Topics
  • Animals
  • Bivalvia (physiology)
  • Calibration
  • Chromatography, High Pressure Liquid
  • Dinoflagellida (chemistry)
  • Marine Toxins (pharmacokinetics)
  • Muscles (metabolism)
  • Shellfish Poisoning

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: