Abstract | BACKGROUND/AIMS:
Pouchitis is one of the most common and debilitating complications of a restorative proctocolectomy. We aimed to analyze the features of pouchitis after restorative proctocolecomy and to determine the risk factors related to its development. METHODS: RESULTS: Among the 169 patients, patients with ulcerative colitis were 64, familial and attenuated adenomatous polyposis 44, Crohn's disease 2, and synchronous or hereditary non-polyposis colorectal cancer were 59 cases. Overall, pouchitis occurred in 15.9% of the patients. The incidence was 37.5% in ulcerative colitis, 1% in non- ulcerative colitis, and 50% in Crohn's disease. In ulcerative colitis group, most of the pouchitis (60.9%) occurred within 6 months after the operation and the remainder experienced the first attack within 1 year after operation. Three patients progressed to chronic pouchitis. There was no association between pouchitis rate and sex, history of smoking, steroid use, temporary ileostomy construction, involvement of appendix or proximal colon, and evidence of indeterminate colitis. Only age was significantly related to the occurrence of pouchitis. CONCLUSIONS:
Pouchitis developed exclusively in ulcerative colitis than other disease groups. Pouchitis occurred most frequently within 6 months after the operation, therefore, it is important to investigate carefully during one year after the operation in patients with ulcerative colitis.
|
Authors | In Ja Park, Chang Sik Yu, Hee Cheol Kim, Young Hak Jung, Kyong Rok Han, Suk Kyun Yang, Jin Cheon Kim |
Journal | The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi
(Korean J Gastroenterol)
Vol. 46
Issue 2
Pg. 99-104
(Aug 2005)
ISSN: 1598-9992 [Print] Korea (South) |
PMID | 16118519
(Publication Type: English Abstract, Journal Article)
|
Topics |
- Adenomatous Polyposis Coli
(complications)
- Adult
- Colitis, Ulcerative
(complications)
- Colorectal Neoplasms
(complications)
- Crohn Disease
(complications)
- Female
- Humans
- Male
- Middle Aged
- Pouchitis
(etiology)
- Risk Factors
|