Oral Candida isolates colonizing or infecting human immunodeficiency virus-infected and healthy persons in Mexico.

Abstract

Oral yeast carriage was studied in 312 Mexican subjects. Candida albicans was the most frequent species, but other Candida spp. were isolated from 16.5 to 38.5% of patients. Colonization did not correlate with CD4+ number or viral load, but highly active antiretroviral therapy reduced the frequency of candidiasis. Most isolates were susceptible to fluconazole, but 10.8% were resistant to one or more azoles.

• Authors: Luis Octavio Sánchez-Vargas, Natalia Guadalupe Ortiz-López, María Villar, María Dolores Moragues, José Manuel Aguirre, Miguel Cashat-Cruz, Jose Luis Lopez-Ribot, Luis Alberto Gaitán-Cepeda, Guillermo Quindós
• Journal: Journal of clinical microbiology (J Clin Microbiol) Vol. 43 Issue 8 Pg. 4159-62 (Aug 2005) ISSN: 0095-1137 [Print] United States
• PMID: 16081965 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Fluconazole

Topics

• Adult
• Aged
• Aged, 80 and over
• Antiretroviral Therapy, Highly Active
• Candida (drug effects, isolation & purification)
• Drug Resistance, Fungal
• Fluconazole (pharmacology)
• HIV Infections (drug therapy, microbiology)
• Humans
• Middle Aged
• Mouth (microbiology)