Obstructive sleep apnea in extremely overweight adolescents undergoing bariatric surgery.

Abstract

OBJECTIVES:

To determine the prevalence of obstructive sleep apnea (OSA) in extremely overweight adolescents and to examine the effect of significant weight loss on OSA severity.

RESEARCH METHODS AND PROCEDURES:

We reviewed the anthropometric and polysomnographic data on all extremely overweight adolescents who underwent laparoscopic Roux en Y gastric bypass surgery at Cincinnati Children's Hospital Medical Center from July 2001 to September 2004. Repeat polysomnograms were performed after significant weight loss. Comparisons were made between pre- and postoperative polysomnographic data.

RESULTS:

Nineteen of 34 patients (55%) who underwent bariatric surgery were diagnosed with OSA. Subsequent to surgery, 10 of these patients returned for follow-up polysomnographic testing. After significant weight loss (mean, 58 kg), OSA severity markedly decreased in all patients (median apnea-hypopnea index at baseline vs. after weight loss, 9.1 vs. 0.65).

DISCUSSION:

Our study indicated that OSA was highly prevalent in extremely overweight adolescents meeting eligibility criteria for bariatric surgery. The significant weight loss after gastric bypass was associated with a marked reduction in OSA severity.

• Authors: Maninder Kalra, Thomas Inge, Victor Garcia, Stephen Daniels, Louise Lawson, Rebecca Curti, Aliza Cohen, Raouf Amin
• Journal: Obesity research (Obes Res) Vol. 13 Issue 7 Pg. 1175-9 (Jul 2005) ISSN: 1071-7323 [Print] United States
• PMID: 16076986 (Publication Type: Journal Article, Research Support, N.I.H., Extramural, Research Support, U.S. Gov't, P.H.S.)

Topics

• Adolescent
• Anastomosis, Roux-en-Y (methods)
• Female
• Gastric Bypass
• Humans
• Male
• Obesity, Morbid (complications, surgery)
• Polysomnography
• Postoperative Period
• Prevalence
• Severity of Illness Index
• Sleep Apnea, Obstructive (epidemiology, etiology, surgery)
• Treatment Outcome
• Weight Loss (physiology)