Outpatient anesthesia for oral surgery in a juvenile with Leigh disease.

Abstract

We report a case of anesthesia for elective outpatient third molar extraction in a juvenile with Leigh disease, a progressive neurodegenerative disorder related to respiratory chain deficiency. This syndrome usually presents in infancy and is characterized by nervous system dysfunction and respiratory abnormalities. Anesthesia has been reported to aggravate respiratory symptoms and frequently precipitate respiratory failure. Preoperative swallowing difficulty or respiratory symptoms should be carefully diagnosed, because they can be a warning sign of postoperative complications or mortality. Adverse effects of anesthesia may quickly lead into metabolic acidosis. Anesthetics should be carefully chosen that do not interfere with mitochondrial respiration, which can lead to lactic acidosis.

• Authors: Zachary Ellis, Charles Bloomer
• Journal: Anesthesia progress (Anesth Prog) Vol. 52 Issue 2 Pg. 70-3 ( 2005) ISSN: 0003-3006 [Print] United States
• PMID: 16048155 (Publication Type: Case Reports, Journal Article)

Chemical References

• Anesthetics, Intravenous
• Anesthetics, Local
• Lidocaine
• Propofol

Topics

• Adolescent
• Ambulatory Surgical Procedures
• Anesthesia, Dental
• Anesthetics, Intravenous (administration & dosage)
• Anesthetics, Local (administration & dosage)
• Dental Care for Chronically Ill
• Elective Surgical Procedures
• Female
• Humans
• Leigh Disease (physiopathology)
• Lidocaine (administration & dosage)
• Mandibular Nerve (drug effects)
• Molar, Third (surgery)
• Nerve Block
• Propofol (administration & dosage)
• Tooth Extraction