Paraneoplastic pemphigus associated with non-Hodgkin B-cell lymphoma and good response to prednisone.

Abstract

Paraneoplastic pemphigus is a life-threatening autoimmune bullous disease associated with neoplasia, generally of lymphoid origin. Immunosuppressive therapy is often disappointing and there are only a few reports of patients surviving more than 2 years. These cases were generally associated with benign neoplasms. We report here the case of a patient with paraneoplastic pemphigus associated with non-Hodgkin B-cell lymphoma who had a surprisingly good response to systemic corticosteroids and remains free of lesions more than 3 years later despite progression of her neoplasm.

• Authors: María Isabel Martínez De Pablo, Pilar Iranzo, José Manuel Mascaró, Alex Llambrich, Manel Baradad, Carmen Herrero
• Journal: Acta dermato-venereologica (Acta Derm Venereol) Vol. 85 Issue 3 Pg. 233-5 ( 2005) ISSN: 0001-5555 [Print] Sweden
• PMID: 16040408 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Glucocorticoids
• Prednisone

Topics

• Aged
• Diagnosis, Differential
• Drug Administration Schedule
• Female
• Glucocorticoids (administration & dosage)
• Humans
• Lymphoma, B-Cell (complications, diagnosis, drug therapy)
• Oral Ulcer (pathology)
• Paraneoplastic Syndromes (complications, diagnosis, drug therapy, pathology)
• Pemphigus (complications, diagnosis, drug therapy, pathology)
• Prednisone (administration & dosage)