Sodium hydroxide chemical matricectomy for the treatment of ingrown toenails: comparison of three different application periods.

Sodium hydroxide matricectomy is a successful method for the treatment of ingrown toenails. This study was designed to evaluate the optimal sodium hydroxide application period providing high success rates with minimal postoperative morbidity.
Sixty-six patients with 225 ingrown nail edges were treated in three groups receiving 30-second, 1-minute, and 2-minute applications of sodium hydroxide. Each patient was reviewed postoperatively for pain, drainage, and tissue damage. The median long-term follow-up period was 14 months.
The success rate of the therapy was 70.9% in the first group, 92.7% in the second group, and 94.4% in the third group. In all groups, about half of the patients experienced minimal pain within 48 hours following the operation, but only in the third group, 20% of the patients had minimal pain, which continued about 1 week. Drainage and tissue damage were minimal or mild in all groups and disappeared within 3 weeks in the first and second groups but were prolonged to 6 weeks in the third group.
The success rate of 30-second application is significantly lower than 1-minute and 2-minute applications. Although the success rates of the latter two procedures are similar, the prolonged healing time is the disadvantage of the 2-minute application. We conclude that 1-minute application of 10% sodium hydroxide is simple, safe, and highly effective for the treatment of ingrown nails.
AuthorsPelin Kocyigit, Seher Bostanci, Esin Ozdemir, Erbak Gürgey
JournalDermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] (Dermatol Surg) Vol. 31 Issue 7 Pt 1 Pg. 744-7; discussion 747 (Jul 2005) ISSN: 1076-0512 [Print] United States
PMID16029698 (Publication Type: Comparative Study, Journal Article)
Chemical References
  • Caustics
  • Sodium Hydroxide
  • Adolescent
  • Adult
  • Aged
  • Caustics (administration & dosage)
  • Child
  • Child, Preschool
  • Drug Administration Schedule
  • Female
  • Humans
  • Male
  • Middle Aged
  • Nails
  • Nails, Ingrown (drug therapy)
  • Sodium Hydroxide (administration & dosage)
  • Time Factors
  • Treatment Outcome

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