HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

[The "self-inflammatory syndrome"].

Abstract
The "self-inflammatory syndrome" gathers diseases all characterized by a recurrent inflammatory syndrome with fever, in the absence of infection or neoplasia. It is based on a genetic support characterized by mutations in genes implied in the inflammatory response and in the activation of the cytokine network. The diseases associated with this syndrome are familial Mediterranean fever (FMF), TRAPS (tumor necrosis factor receptor super family 1 A-associated periodic syndrome), familial cold urticaria, the Muckle-Wells syndrome, the hyper IgD syndrome and CINCA. The clinical symptoms of all these diseases include in the auto-inflammatory syndrome are quite similar: recurrent attacks, with fever, articular, abdominal, cutaneous symptoms, and an inflammatory syndrome.
AuthorsA Pradalier, A Cauvain
JournalPathologie-biologie (Pathol Biol (Paris)) Vol. 54 Issue 3 Pg. 171-8 (Apr 2006) ISSN: 0369-8114 [Print] France
Vernacular TitleLe syndrome auto-inflammatoire.
PMID16019157 (Publication Type: English Abstract, Journal Article, Review)
Chemical References
  • Tumor Necrosis Factor-alpha
Topics
  • Familial Mediterranean Fever (genetics)
  • Genes, Recessive
  • Humans
  • Inflammation (genetics)
  • Periodicity
  • Recurrence
  • Syndrome
  • Tumor Necrosis Factor-alpha (genetics)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: