HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Long-term efficacy of distal splenorenal shunt with splenopancreatic and gastric disconnection for esophagogastric varices in patients with idiopathic portal hypertension.

Abstract
Idiopathic portal hypertension (IPH) requires invasive measures to prevent rupture and bleeding of esophagogastric varices. However, the long-term results of shunt surgery for IPH have not been reported. In particular, the pros and cons of surgery that preserves the spleen and its long-term hematologic effects have not been described. The records of 15 patients who underwent distal splenorenal shunt with splenopancreatic and gastric disconnection (DSRS with SPGD) for IPH between 1983 and 1998 was reviewed retrospectively. One patient died within 3 years of surgery, for a 3-year survival rate of 93%; the 10-year survival rate was 64%. Three patients (18%) suffered rebleeding from esophagogastric varices. The white blood cell and platelet counts were higher 3-5 years and 7-13 years postoperatively compared with preoperative values. Four of five patients who underwent postoperative computed tomography had a smaller spleen postoperatively. DSRS with SPGD provides long-term hemostasis for esophagogastric variceal bleeding in IPH and alleviates hypersplenism. DSRS with SPGD is an effective treatment for patients with IPH in whom long-term survival is expected.
AuthorsRyunosuke Hase, Satoshi Hirano, Satoshi Kondo, Shunichi Okushiba, Toshiaki Morikawa, Hiroyuki Katoh
JournalWorld journal of surgery (World J Surg) Vol. 29 Issue 8 Pg. 1034-6; discussion 1037 (Aug 2005) ISSN: 0364-2313 [Print] United States
PMID15977080 (Publication Type: Journal Article)
Topics
  • Adolescent
  • Adult
  • Aged
  • Esophageal and Gastric Varices (etiology, surgery)
  • Female
  • Humans
  • Hypertension, Portal (complications)
  • Male
  • Middle Aged
  • Retrospective Studies
  • Splenorenal Shunt, Surgical (methods, mortality)
  • Survival Analysis
  • Treatment Outcome

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: