Abstract | OBJECTIVE: METHODS AND RESULTS: CONCLUSIONS: n-3 and n-6 PUFA supplementation retarded the development of atherosclerosis in LDLR(-/-) mice, with a stronger effect seen with n-3 PUFA. There was an important strain-dependence of the effect, with no protection against atherosclerosis in apoE(-/-) mice.
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Authors | Antonella Zampolli, Anette Bysted, Torben Leth, Alicja Mortensen, Raffaele De Caterina, Erling Falk |
Journal | Atherosclerosis
(Atherosclerosis)
Vol. 184
Issue 1
Pg. 78-85
(Jan 2006)
ISSN: 0021-9150 [Print] Ireland |
PMID | 15946668
(Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Cholesterol, LDL
- Fish Oils
- Triglycerides
- Corn Oil
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Topics |
- Animals
- Aorta, Thoracic
(pathology)
- Atherosclerosis
(blood, pathology, prevention & control)
- Cholesterol, LDL
(blood)
- Corn Oil
(pharmacology)
- Dietary Supplements
- Disease Models, Animal
- Disease Progression
- Female
- Fish Oils
(therapeutic use)
- Male
- Mice
- Mice, Knockout
- Triglycerides
(blood)
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