Therapeutic effects of laser photocoagulation and/or vitrectomy in Eales' disease.

Abstract

PURPOSE:

To determine visual outcomes and regression of retinal neovascularization following laser photocoagulation and/or vitrectomy in eyes with Eales' disease.

METHODS:

In a retrospective noncomparative study, the authors reviewed the existing data of 67 eyes of 54 patients with a diagnosis of Eales' disease who had undergone laser photocoagulation and/or vitrectomy based on their clinical presentations. Main outcome measures were visual acuity changes and regression of retinal neovascularization of the eyes following treatment.

RESULTS:

Both laser therapy and vitrectomy improved visual acuity and induced regression of retinal neovascularization. Forty-three eyes had undergone laser therapy; their rate of visual acuity 320/30 improved from 53% before treatment to 60% after treatment. Twenty-four eyes had undergone vitrectomy; rate of visual acuity 320/30 improved from 13% before surgery to 38% after surgery. In eyes that had undergone laser therapy, additional laser therapy controlled recurrent neovascularization in 47% of the eyes, but ultimately, 12% of them required vitrectomy. In the primary vitrectomized group, additional required treatment was repeat vitrectomy in 21%, and/or laser therapy in 29% of the eyes.

CONCLUSIONS:

Although laser photocoagulation should be the first line of treatment in Eales' disease, it cannot always induce regression of retinal neovascularization. In such cases vitrectomy may further enhance therapeutic success.

• Authors: M H Dehghan, H Ahmadieh, M Soheilian, M Azarmina, A Mashayekhi, J Naghibozakerin
• Journal: European journal of ophthalmology (Eur J Ophthalmol) 2005 May-Jun Vol. 15 Issue 3 Pg. 379-83 ISSN: 1120-6721 [Print] United States
• PMID: 15945008 (Publication Type: Journal Article)

Topics

• Adult
• Female
• Fluorescein Angiography
• Follow-Up Studies
• Fundus Oculi
• Humans
• Laser Coagulation
• Male
• Middle Aged
• Retinal Neovascularization (physiopathology)
• Retinal Vasculitis (complications, pathology, surgery)
• Retrospective Studies
• Secondary Prevention
• Treatment Outcome
• Visual Acuity
• Vitrectomy