[Lumbar epidural morphine for postoperative analgesia in children undergoing Nuss procedure].

Abstract

BACKGROUND:

We examined the effects of lumbar epidural morphine for postoperative analgesia in children after the Nuss procedure for funnel chest.

METHODS:

An epidural catheter was inserted from the L 3-4 interspace preoperatively (epidural group). Epidural morphine 30 microg x kg(-1) was given at the beginning of the operation. Postoperatively, epidural morphine 3 microg x kg(-1) x hr(-1) was infused. The frequency of demand for postoperative analgesia was retrospectively compared with that of children who had not received epidural morphine (control group).

RESULTS:

On the 0th postoperative day, the epidural group required fewer analgesics than the control group (0.50+/-0.30 vs. 2.50+/-1.00 x day(-1)). However, after the 1st postoperative day, the demand for analgesia did not differ between the two groups.

CONCLUSIONS:

Epidural morphine 30 microg x kg(-1) given at the beginning of operation provided effective analgesia on the 0th postoperative day after the Nuss procedure. However, epidural infusion of morphine 3 microg x kg(-1) x hr(-1) was not effective after the 1st postoperative day. Further study is needed to determine the lumbar epidural infusion dose of morphine adequate for use after the Nuss procedure.

• Authors: Nobutaka Kariya, Yuka Inoue, Wakaba Minami, Yoshikazu Ikeda, Shinichi Nishi, Kiyonobu Nishikawa, Akira Asada
• Journal: Masui. The Japanese journal of anesthesiology (Masui) Vol. 54 Issue 5 Pg. 496-9 (May 2005) ISSN: 0021-4892 [Print] Japan
• PMID: 15915747 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Morphine

Topics

• Analgesia, Epidural (methods)
• Child
• Child, Preschool
• Funnel Chest (surgery)
• Humans
• Lumbosacral Region
• Morphine (administration & dosage)
• Pain, Postoperative (therapy)