Electrochemical study of breast cancer cells MCF-7 and its application in evaluating the effect of diosgenin.

Abstract	The electrochemical behavior of breast cancer cells was studied on a graphite electrode by cyclic voltammetry (CV) and potentiometric stripping analysis (PSA). In both cases, only one oxidative peak at approximately +0.75 V was observed. The peak area in PSA was used to study the growth of the cells and the effect of diosgenin on MCF-7 cells. The results showed that diosgenin can effectively inhibit the viability and proliferation of the breast cancer cells.
Authors	Jia Li, Xuanmin Liu, Manli Guo, Yingju Liu, Shanchao Liu, Shouzhuo Yao
Journal	Analytical sciences : the international journal of the Japan Society for Analytical Chemistry (Anal Sci) Vol. 21 Issue 5 Pg. 561-4 (May 2005) ISSN: 0910-6340 [Print] Switzerland
PMID	15913148 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
Chemical References	Antineoplastic Agents Indicators and Reagents Trypan Blue Diosgenin
Topics	Antineoplastic Agents (pharmacology) Breast Neoplasms (chemistry, drug therapy) Cell Line, Tumor Cell Proliferation Diosgenin (pharmacology) Electrochemistry Female Humans Indicators and Reagents Potentiometry Trypan Blue

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