Effect of low-dose, short-duration creatine supplementation on anaerobic exercise performance.

Abstract

To examine the efficacy of a low-dose, short-duration creatine monohydrate supplement, 40 physically active men were randomly assigned to either a placebo or creatine supplementation group (6 g of creatine monohydrate per day). Testing occurred before and at the end of 6 days of supplementation. During each testing session, subjects performed three 15-second Wingate anaerobic power tests. No significant (p > 0.05) group or time differences were observed in body mass, peak power, mean power, or total work. In addition, no significant (p > 0.05) differences were observed in peak power, mean power, or total work. However, the change in the rate of fatigue of total work was significantly (p < 0.05) lower in the creatine supplementation group than in the placebo group, indicating a reduced fatigue rate in subjects supplementing with creatine compared with the placebo. Although the results of this study demonstrated reduced fatigue rates in patients during high-intensity sprint intervals, further research is necessary in examining the efficacy of low-dose, short-term creatine supplementation.

• Authors: Jay R Hoffman, Jeffrey R Stout, Michael J Falvo, Jie Kang, Nicholas A Ratamess
• Journal: Journal of strength and conditioning research (J Strength Cond Res) Vol. 19 Issue 2 Pg. 260-4 (May 2005) ISSN: 1064-8011 [Print] United States
• PMID: 15903359 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)

Chemical References

• Creatine

Topics

• Adult
• Anaerobic Threshold (drug effects, physiology)
• Area Under Curve
• Creatine (administration & dosage)
• Dietary Supplements
• Dose-Response Relationship, Drug
• Drug Administration Schedule
• Exercise (physiology)
• Humans
• Male
• Muscle Fatigue (drug effects, physiology)
• Muscle, Skeletal (drug effects, physiology)
• Running (physiology)
• Task Performance and Analysis
• Treatment Outcome