Abstract |
Fifty patients suffering from functional dyspepsia have been treated in a double-blind study either with 1-sulpiride (75 mg die per os) or with metoclopramide (30 mg die per os) for 30 days. The frequency and severity of the symptoms in the two patient groups were similar. The administration of either drug was followed by a reduction of the symptoms, but 1-sulpiride was more effective on nausea, headache, pyrosis, epigastric pain, and showed an earlier effect than metoclopramide in inducing total regression of symptoms.
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Authors | G Macarri, L Biasi, E Brunelli, L Marucci, G Svegliati Baroni |
Journal | Minerva medica
(Minerva Med)
Vol. 83
Issue 5
Pg. 295-8
(May 1992)
ISSN: 0026-4806 [Print] Italy |
Vernacular Title | L-sulpiride contro metoclopramide nella dispepsia funzionale: studio randomizzato in doppio cieco. |
PMID | 1589135
(Publication Type: Clinical Trial, Comparative Study, English Abstract, Journal Article, Randomized Controlled Trial)
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Chemical References |
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Topics |
- Adult
- Aged
- Double-Blind Method
- Dyspepsia
(diagnosis, drug therapy)
- Female
- Humans
- Male
- Metoclopramide
(therapeutic use)
- Middle Aged
- Sulpiride
(therapeutic use)
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