Abstract | OBJECTIVES: METHODS: We present 2 cases and review the literature with an emphasis on the fertility potential. RESULTS: Germ cells were present in the testicular biopsy of an infant with cryptorchidism but not in the adolescent with a varicocele. The latter biopsy showed tubular sclerosis. CONCLUSIONS: The fertility potential of patients with Klinefelter syndrome and cryptorchidism may be preserved or enhanced by an early orchiopexy. However, the potential benefit of ligation of internal spermatic veins in patients with Klinefelter syndrome and a varicocele warrants further study. Cryopreservation should be considered early in adolescence or adulthood as germ cells become depleted at an accelerated rate after puberty.
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Authors | Blanca M Brandes, Hrair-George O Mesrobian |
Journal | Urology
(Urology)
Vol. 65
Issue 5
Pg. 976-9
(May 2005)
ISSN: 1527-9995 [Electronic] United States |
PMID | 15882735
(Publication Type: Case Reports, Journal Article, Review)
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Topics |
- Adolescent
- Cryptorchidism
(complications, diagnosis, surgery)
- Humans
- Infant
- Infertility, Male
(etiology)
- Klinefelter Syndrome
(complications, pathology)
- Male
- Testis
(pathology)
- Varicocele
(complications, diagnosis, surgery)
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