Abstract | BACKGROUND: METHODS: A randomized, controlled trial of dietary supplementation with omega-3 and omega-6 fatty acids, compared with placebo, was conducted with 117 children with DCD (5-12 years of age). Treatment for 3 months in parallel groups was followed by a 1-way crossover from placebo to active treatment for an additional 3 months. RESULTS: No effect of treatment on motor skills was apparent, but significant improvements for active treatment versus placebo were found in reading, spelling, and behavior over 3 months of treatment in parallel groups. After the crossover, similar changes were seen in the placebo-active group, whereas children continuing with active treatment maintained or improved their progress. CONCLUSIONS:
Fatty acid supplementation may offer a safe efficacious treatment option for educational and behavioral problems among children with DCD. Additional work is needed to investigate whether our inability to detect any improvement in motor skills reflects the measures used and to assess the durability of treatment effects on behavior and academic progress.
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Authors | Alexandra J Richardson, Paul Montgomery |
Journal | Pediatrics
(Pediatrics)
Vol. 115
Issue 5
Pg. 1360-6
(May 2005)
ISSN: 1098-4275 [Electronic] United States |
PMID | 15867048
(Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
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Chemical References |
- Fatty Acids, Omega-3
- Fatty Acids, Omega-6
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Topics |
- Attention Deficit Disorder with Hyperactivity
(drug therapy)
- Child
- Child Behavior
(drug effects)
- Cross-Over Studies
- Dietary Supplements
- Fatty Acids, Omega-3
(therapeutic use)
- Fatty Acids, Omega-6
(therapeutic use)
- Humans
- Language Arts
- Motor Skills
(drug effects)
- Motor Skills Disorders
(drug therapy)
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