A comparison of Syntocinon infusion with prostaglandin vaginal pessaries when spontaneous rupture of the membranes occurs without labour after 34 weeks gestation.

Abstract

In a prospective randomized trial of 106 patients who had spontaneously ruptured their membranes greater than or equal to 4 hours in the absence of labour, vaginal prostaglandin E2 pessaries and intravenous Syntocinon were compared. There was no significant difference in the treatment to delivery times between the 2 groups. The number of operative deliveries in each group were comparable. No untoward side-effects were noted. The use of vaginal prostaglandin E2 tablets appears to be a safe alternative to Syntocinon for induction of labour when spontaneous rupture of membranes has occurred in the absence of uterine contractions.

• Authors: J Rymer, A Parker
• Journal: The Australian & New Zealand journal of obstetrics & gynaecology (Aust N Z J Obstet Gynaecol) Vol. 32 Issue 1 Pg. 22-4 (Feb 1992) ISSN: 0004-8666 [Print] Australia
• PMID: 1586329 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)

Chemical References

• Oxytocin
• Dinoprostone

Topics

• Dinoprostone (administration & dosage)
• Female
• Fetal Membranes, Premature Rupture (therapy)
• Humans
• Infusions, Intravenous
• Labor, Induced (methods)
• Oxytocin (administration & dosage)
• Pessaries
• Pregnancy
• Prospective Studies