Optical coherence tomography in presumed congenital simple hamartoma of retinal pigment epithelium.

Abstract

PURPOSE:

To report the optical coherence tomography (OCT) findings in two cases of presumed congenital simple retinal pigment epithelial (RPE) hamartoma.

DESIGN:

Observational case report.

METHODS:

Fundus examination, fluorescein angiography, ultrasonography, and OCT were done on two cases of simple RPE hamartoma.

RESULTS:

A heavily pigmented solitary macular lesion was noted in the right eye of a 22-year-old man and a 55-year-old woman. The young man had a foveal lesion and a vision of 10/200; the woman with eccentric lesion had a vision of 20/20. The lesions blocked fluorescence on angiogram; sonography showed hyper-reflective nodules. OCT demonstrated full-thickness retinal replacement, complete optical shadowing, and abrupt margins of the lesion in both the cases, and vitreomacular adhesion at the temporal margin of the foveal lesion.

CONCLUSIONS:

Congenital simple RPE hamartoma may rarely occur at the foveal center, resulting in poor visual acuity. OCT is a useful non-invasive adjunct for diagnosis of this rare tumor and may reveal additional features like vitreoretinal adhesion.

• Authors: Dhananjay Shukla, Shamik Ambatkar, Jitendra Jethani, Ramasamy Kim
• Journal: American journal of ophthalmology (Am J Ophthalmol) Vol. 139 Issue 5 Pg. 945-7 (May 2005) ISSN: 0002-9394 [Print] United States
• PMID: 15860319 (Publication Type: Case Reports, Journal Article)

Topics

• Adult
• Diagnostic Techniques, Ophthalmological
• Female
• Fluorescein Angiography
• Hamartoma (congenital, diagnosis)
• Humans
• Male
• Middle Aged
• Pigment Epithelium of Eye (pathology)
• Retinal Diseases (congenital, diagnosis)
• Tomography, Optical Coherence